This article describes the knowledge-based system TheMPO (Therapy Manage- ment in Pediatric Oncology), which supports protocol-directed therapy planning and configuration in pediatric oncology. TheMPO provides a semantic network controlled by graph-grammars to cover the different types of knowledge relevant in the domain, and offers a suite of acquisition tools for knowledge base author- ing. Medical problem solvers, operating on the oncological network, reason about adequate therapeutic and diagnostic time-tables for a patient. Furthermore, a cor- responding patient record, also based on semantic networks and graph-grammars, has been implemented to represent the course of therapy of an oncological patient.
Appeared / Erschienen in:
Computers in Biology and Medicine, vol. 27(3), 1997:177-200
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